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Increasing production capacity may necessitate the facility to cater for higher hazardous area category (e.g., H-Occupancy) design features, such as specialized building construction and potential blast zones. [...]an assessment should cover: * Quantification of flammable material use for production steps, including buffer preparation and LNP storage * Equipment and facility cleaning strategies that contribute to the facility flammable materials inventory * Impact of HVAC design to avoid hazardous atmospheres (e.g., full fresh air), use of local exhaust ventilation (LEV) or fume hoods * Solvent distribution methods (e.g., closed solvent delivery and waste removal systems) * Location of solvent bulk storage outside of the processing area/ facility, and piping in what is necessary plus removing spent solvent in a timely manner (e.g., piped transfer to a waste tank for removal by a specialist contractor). At present, the process cannot be fully single-use, so thought needs to be put into the cleaning and sterilization processes, plus the analytical support infrastructure needed for reusable product-contact surfaces. [...]it is recommended that for each mRNA project, consideration is given to the following aspects to determine the link between the equipment available and the facility design: * Need for custom/proprietary equipment * Independent production rooms with "through-wall" buffer transfer through iris ports in from logistics corridor (Buffer Prep/Hold) * Room electrical classification needs versus process step. * Equipment selection versus electrical and fire code requirements * Benefits and limitations of implementing single-use technologies, given that the process will be hybrid (with stainless steel). [...]the limited capacity for outsourcing of supporting functions, such as facility environmental monitoring or product sterility testing, should be considered during concept design.
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Introduction. Since March 2020, the introduction of a self-isolation regime and significant restrictions on personal contacts at work and school in connection with the COVID-19 pandemic has led to an expansion of the introduction of information technologies and a sharp restriction of direct interpersonal communication. The introduction of these restrictions has had a stressful effect on the body of both workers and students of various age groups, including young people. For a successful analysis of the impact of COVID-19 restrictions on the psychophysiological state of these categories of young workers and students, it seems appropriate to assess the state of maladaptation, self-assessment of nervous and somatic well-being. The study aims to assess the impact on the adaptive psychophysiological parameters of young trade workers and students of the changed working and study conditions against the background of the COVID–19 epidemic situation (self-isolation). Materials and methods. The object of the study was two groups of people who have a wide range of communication with colleagues and people around them, but differ in the content of their activities: students and trade workers. Scientists have conducted the study in two stages: before the pandemic (2013) and during the pandemic (December 2020) due to drastic changes in the algorithm of existence and work/study. We have examined 119 students aged 20–24 years (RGSU). There were 61 people at the first stage of the study (2013), there were 58 people at the second stage (2020, December). The second group (trade workers): 66 people aged 20–29 years. At the first stage of the study (2013), 34 people were included, at the second stage — 32 people. Experts have carried out the assessment of the psychophysiological parameters of the examined according to the questionnaire of neuropsychiatric maladjustment (ONPD). The condition for inclusion in the groups in 2020–2021 is the absence of a history of transferred COVID-19. Results. During the tense epidemic situation (2019-2021), against the background of the spread of COVID-19 and forced self-isolation of all population groups, the lifestyle has radically changed. Face-to-face communication has been minimized, but communication using information technology in all spheres of life (daily life, study, work) has increased dramatically. The researchers found that among the surveyed population groups (students and sales workers), the spread of signs of mental discomfort increased. Limitations. The study was limited to a sample of age groups: 20–24 years for students, 20–29 years for trade workers (in both periods). Conclusion. The calculation of the odds ratio (OR) allowed us to establish with a high degree of confidence that signs of mental discomfort, including asthenic and depressive signals, were significantly more often recorded during the period of self-isolation in both study groups: for students who are on distance learning (December 2020 compared to 2013): the coefficient of OR=5.4, (χ2=14.7;p<0.001);for sales workers: coefficient OR=15.0;(χ2=9.5;p<0.001). Ethics. Questions whose content does not meet ethical standards were not included in the study, as a result of which the conclusion of the biomedical ethics committee or other documents was not required. © 2023, Izmerov Research Institute of Occupational Medicine. All rights reserved.
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Background. Since the start of the COVID-19 pandemic, Chad has had 7,417 confirmed cases and 193 deaths, one of the lowest in Africa. Objective. This study assessed SARS-CoV-2 immunity in N'Djamena. Methods. In August-October 2021, eleven N'Djamena hospitals collected outpatient data and samples. IgG antibodies against SARSCoV- 2 nucleocapsid protein were identified using ELISA. "Bambino Gesu" Laboratory, Rome, Italy, performed external quality control with chemiluminescence assay. Results. 25-34-year-old (35.2%) made up the largest age group at 31.9 12.6 years. 56.4% were women, 1.3 women/men. The 7th district had 22.5% and the 1st 22.3%. Housewives and students dominated. Overall seroprevalence was 69.5% (95% CI: 67.7-71.3), females 68.2% (65.8-70.5) and males 71.2% (68.6-73.8). >44-year-old had 73.9% seroprevalence. Under-15s were 57.4% positive. Housewives (70.9%), civil servants (71.5%), and health workers (9.7%) had the highest antibody positivity. N'Djamena's 9th district had 73.1% optimism and the 3rd district had 52.5%. Seroprevalences were highest at Good Samaritan Hospital (75.4%) and National General Referral Hospital (74.7%). Conclusion. Our findings indicate a high circulation of SARS-CoV- 2 in N'Djamena, despite low mortality and morbidity after the first two COVID-19 pandemic waves. This high seroprevalence must be considered in Chad's vaccine policy.
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Background: The Covid-19 pandemic has had a significant impact on nurses. Nurses as workers face various health hazards in the workplace (hospital). Nurses are a group at risk of contracting the virus when providing nursing care to Covid-19 patients. This study aimed to determine the meaning of nurses' experience as workers during the Covid-19 pandemic. Design: This research is qualitative research with a descriptive phenomenological approach. Methods: Data collection was done using in-depth interviews with online interviews using the zoom application. The interview data were analyzed using the Colaizzi method. Results: The results of this study identified four main themes, namely feelings of insecurity, dangers faced by nurses, active nurses in preventing transmission, and meaning for nurses. Conclusion: This study provides information that nurses during the Covid-19 pandemic face various health hazards. The implications of this research, as input to occupational health nursing science regarding the danger nurses faced during the Covid-19 pandemic. Suggestions from this research are expected to optimize efforts to promote and protect the health and safety of nurses during the Covid-19 pandemic. © Asia Pacific Higher Learning Sdn Bhd., Lincoln University College. All Rights Reserved.
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COVID-19 transformed frontline anti-violence workers' organizational routines by transitioning to virtual formats, decreasing face-to-face interactions, and shifting client needs. To address ever-changing workplace stressors, service providers adapted and/or modified coping mechanisms. In this paper, we analyze interviews with 23 anti-violence workers in the US Great Plains region, focusing on tactics used to avoid burnout and meet client needs. We discuss how workplace pace, direct-action coping practices, and a lack of inter/intra-agency social support impact how workers do their necessary jobs. Though some challenges were pervasive pre-pandemic, anti-violence workers' experiences also highlight how "post-COVID-19” workplaces must adequately support staffers. © The Author(s) 2023.
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IMPACTThis article explores the consequences of emotional labour on UK NHS ambulance staff and their response to the Covid-19 pandemic. It highlights the challenges faced by ambulance crews while dealing with their emotional labour within the context of organizational settings. Research findings also explain the importance of emergency responders' psychosocial wellbeing. The article has clear relevance as to how frontline staff manage their emotional labour in other emergency service settings, such as the police and fire and rescue services.Alternate :Managing emotions are essential aspect of many jobs, and frontline healthcare workers have to manage and control their emotions while caring for critically ill patients and working in an emotionally-charged dynamic environment;this was particularly the case during Covid-19. Ambulance workers are an important group in this respect but they are currently under-researched. Evidence behind this article comes from data collected from an NHS ambulance trust in England. One of the key contributions of this article is to highlight how frontline ambulance professionals manage their emotional labour while working within the stipulations of organizational constraints.
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Under the Chinese "Zero-COVID” policy, many laborers were forced out of work. Participating in educational compensation can effectively help unemployed laborers achieve re-employment. This paper selected Jining, Shandong Province, as the research area, analyzed the data using a questionnaire survey and key interviews, and observed factors that affect and change willingness to receive educational compensation (WTEC) and the willingness to accept the training duration (WTTD) of unemployed laborers. The study found that 77.78% of unemployed laborers are willing to receive educational compensation, and the WTTD is 12.05 days. Among them, eight factors affect WTEC, such as the years of education, the duration of unemployment, whether there are dependents in the family, and the family's size. Nine factors such as gender, age, education, unemployed duration, dependents, and other supportable incomes affect WTTD. Based on this, by taking measures from the government and laborers, WTEC and WTTD can be improved, and then the rate of re-employment can be enhanced, and finally, the employment problem can be ameliorated.
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This article centres on a qualitative interview extract, the ‘Story of the Pebble', in which a West African Hospital Social Worker Ado, working in a UK context, and identifying as a Shaman, describes successfully trusting his instincts to create a symbol for a dying patient. Despite criticisms from colleagues, Ado's capacity to understand his patients needs are justified both before and after her death.The article discusses significant themes from the interview extract, including the meaning of professionalism, practice wisdom and cultural influences in a UK social work context, as well as through Ado's heritage and identification as a Shaman. The article considers holistic patient care in a medical context and suggests this has some useful lessons for social workers, particularly those involved with dying people. Although the extract, and wider research study from which it is drawn, pre-date the Covid 19 pandemic, this is referenced throughout, linking the interview extract to ways of helping practitioners and educators to consider people holistically at end of life. AD -, Chichester, UK ;, Chichester, UK
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In the aftermath of the COVID-19 pandemic and amid the present reconfiguring of corporate purpose, there is an opportunity to realign actions focused on prolonging working lives. We put forward a transformative agenda concerned with workforce ageing that aligns with contemporary expectations regarding sustainability, inequality, and emerging conceptualisations of management. In this article, the new concept of Common Good human resource management (HRM) is utilised as a potential means of encouraging business responses focused on grand challenges such as population ageing. We suggest how these principles might be applied to the issue of managing age in workplaces, to recast debate about issues of age and work, to be used as an advocacy tool encouraging employer engagement, while providing a framework that might direct organisational leadership. © The Author(s), 2023. Published by Cambridge University Press on behalf of UNSW Canberra.
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COVID-19 is a widespread contagious viral infection that can severely affect the respiratory system. Although many people recover from using the disease without special care or treatment, pregnant women are particularly vulnerable to pulmonary infections due to their hangers systems system and physiology. To investigate the treatment provided to pregnant women who are PCR-positive for COVID-19 in their early three months of pregnancy, a reanalyzed analyzed data from 84 participants who received treatment at Tangerang Regional Hospital in 2 study was the study conducted based on an ases of observational investigation with a cross-sectional approach. It assembled the data for analysis of the chi-square test. The results showed that 92.9% of participants underwent a cesarean section, while the remaining 7.1% were discharged after giving birth typically or recovering. Additionally, the study did not find any correlation between factors such as age, education, work, gravida, ANC visit, and the impact of COVID-19 on the third trimester of pregnancy at Tangerang Hospital in 2022. The study recommends that pregnant women seek information about pregnancy care from healthcare providers, particularly midwives, posyandu officers, and the media, to make well-known decisions about their health and well-being during this critical period, ensuring a safe and healthy pregnancy outcome.
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Background: The 2019 coronavirus disease (COVID-19) outbreak, which was brought on by the SARS-CoV-2 novel coronavirus, has had a significant negative influence on our environment and exposed health-care personnel to a new level of risk. Very few studies have addressed the disturbances in the sleep quality of healthcare workers during COVID-19 pandemic. Aim and Objectives: The primary objective of the study was to examine the sleep quality of frontline healthcare workers during COVID-19 pandemic in a tertiary care center in northern Kerala. Material(s) and Method(s): Healthcare workers belonging to a tertiary care center were invited to participate in the study. An online questionnaire including sociodemographics, Pittsburgh sleep quality index, and Insomnia severity index was used to evaluate sleep disturbances in healthcare workers. Univariate and bivariate analysis of the results were done to identify the predictors of poor sleep quality. Result(s): A total of 250 frontline healthcare workers were enrolled in the study, out of which 243 participants provided usable responses. About 27.6% of health workers showed features of poor sleep quality. The prevalence rate of poor sleep quality was highest among nurses, 55.2% followed by doctors and ambulance drivers, 22.4% and 11.9%, respectively. About 17.7% of the study population had subthreshold insomnia and 1.2% had clinical insomnia of moderate intensity. Conclusion(s): The prevalence of poor sleep quality is high among healthcare workers confronting COVID pandemic. This study emphasizes the need to implement specific protective measures for maintaining the sleep quality and decreasing stress among frontline health care workers during pandemics.Copyright © 2023, Mr Bhawani Singh. All rights reserved.
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A pandemic is a complex phenomenon that requires multi-directional corrective actions and, above all, preventive measures. Managing crises such as the COVID-19 pandemic has proven to be the biggest challenge facing healthcare organizations. In the process of ensuring a safe hospital environment for patients and staff, various models and adequate approaches to crisis management were applied. In order to explore the opinion of health care managers on the challenges and practices of providing a safe hospital environment in the management of the COVID-19 pandemic, a qualitative survey - a semi-structured interview - was conducted among 35 health care managers. Based on the results of the interviews with head and senior nurses, the main themes related to "challenges" and "practices" during the pandemic related to the practice of health care professionals were identified. Challenges include: developing and implementing measures to manage safe hospital environment during the COVID-19 pandemic;staff shortages and psychological problems. Practices include changes in nurses' work schedules, nurse rotation, staff training, organizational support. Healthcare managers have provided new and safe practices for managing staff and the environment during the COVID-19 pandemic. The results of this study show that healthcare managers perceive management during the COVID-19 pandemic differently than other crises. In their opinion, managing in these difficult conditions is very complex and requires greater flexibility on the part of managers in accordance with constantly changing circumstances.
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Background: Studies show that wearing personal protective equipment (PPE) for long periods of time can lead to discomfort such as headaches, which could affect the performance of healthcare workers. The aim of this study was to determine the prevalence and risk factors of headaches related to PPE in healthcare workers at a COVID-19 referral hospital. Methods: A cross-sectional study was conducted involving 174 healthcare workers in a COVID-19 referral hospital in Bali. We conducted interviews using a questionnaire that consisted of three main parts: characteristics of the subjects, PPE usage, and PPE-associated headaches. A multiple logistic regression was used to analyze the data. Results: The analysis results showed that the PPE-associated headaches had a prevalence of 63.8% and were gradual in onset, pressure-like in quality (46%), and mild in intensity (80.1%). PPE level III-associated headache was the most common type. The majority of the participants had headaches up to 6 hours after using the protective gear, but improving within 15-30 minutes of removal and/or after pharmacotherapy. A Chi-squared analysis showed a statistically significant association between duration of PPE use, working units, and PPE levels (p<0.05). A logistic regression analysis found a significant relationship between PPE level and headache occurrence (OR=4.826;95%CI: 2.433-9.572;p<0.001). Conclusion: The frequency of PPE-associated headache was high and the PPE level was a risk factor of headache among healthcare workers. Better strategies are needed to reduce the duration of PPE exposure so that the work performance and quality of life of healthcare workers are not significantly affected.
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Background: Healthcare workers (HCWs) in India are facing physical and psychological pressure. The pandemic has significant psychological impacts. Hence, we wanted to assess the mental stress and social stress among HCWs during the second wave of COVID-19. Aim and Objectives: Assessment of the mental distress among HCWs of tertiary care level institution during second wave of COVID-19 with the following objectives: (1) To know the sociodemographic characteristics of the HCWs of tertiary care center and (2) to assess the psychological stress among healthcare workers of a tertiary health center. Material(s) and Method(s): It is a cross-sectional and observational study conducted in hospital setting, in a tertiary care setting. Data were collected from 196 HCWs of the institute. Institutional ethical clearance was taken before the study. Structured questionnaire included sociodemographic variables, work-related variables, and variables to assess social stress. We used hospital anxiety and depression scoring questionnaire to assess anxiety and depression. Data were collected through personal interviews and online through Google forms after taking informed consent. Descriptive statistics and Chi-square tests are used analyzed using Statistical Package for the Social Sciences Version 21 for Statistical analysis. Result(s): A total of 196 HCWs, 121 doctors, 74 nursing staff, and one ward staff participated in the study. Nursing staff were at higher risk for anxiety and depression, that is, 29% and 25% than others. Females were slightly more anxious (29%) and depressed (17%) than males. HCWs who are Muslim by religion were at more mental distress. Media exposure of more than 3 h had increased risk of mental distress. HCWs with other frontline COVID warrior as a partner were both anxious (40%) and depressed (20%). Anxiety (35%) was more among those who's family members got COVID positive. About 25% of them faced social stigma, 55% of them faced issue of isolation with in the community, and 14% of them faced acts of violence which is unacceptable. Conclusion(s): Although its second wave HCWs are still having psychological distress which needs to be addressed. Social stress that they are facing is significant and is associated with higher anxiety and depression, which has to be taken seriously.Copyright © 2023, Mr Bhawani Singh. All rights reserved.
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Introduction. The high risk of infection of healthcare workers dictates the need to study their working conditions during the COVID-19 pandemic. The study aims to research the working conditions of medical workers during the COVID–19 pandemic in multidisciplinary medical and preventive organizations. Materials and methods. Analysis of working conditions of medical workers of medical and preventive organizations. The study design is a closed population (four medical institutions were randomly selected), a target group (doctors and nurses). The authors analyzed the staffing table and 16 reports on a special assessment of working conditions at 1,251 workplaces (1,845 medical workers, of which 787 doctors, 1,058 nurses). Statistical analysis included: standard methods of descriptive statistics, determination of relationships by logistic regression (odds ratios (OR) and 95% confidence intervals (OR CI)). p<0.05 was taken as the critical level of significance. Results. The largest number of ill medical workers provided assistance to patients without signs of COVID-19 both in hospitals (86.06% of doctors, 85.85% of nurses) and in outpatient polyclinic treatment and prevention organizations (90.31% of doctors, 92.05% of nurses). The probability of getting sick COVID-19 was maximum in an infectious diseases hospital (compared with emergency departments OR 2.049;95% OR CI 1.194–4.608 and diagnostic and treatment units of medical institutions OR 3,057;95% OR CI 1,876–4,98). The workplaces of medical workers who have undergone COVID-19 in infectious diseases hospitals and specialized teams are classified as harmful class 1–3 degrees, and workers are classified as high occupational risk groups according to SARS-CoV-2. The probability of getting sick with COVID-19 is significantly higher when in contact with pathogens of infectious diseases (class of working conditions 3.3 compared to 3.1 or 3.2). Conclusion. The workplaces of medical workers who have undergone COVID-19 in infectious diseases hospitals and specialized brigades are classified as harmful class of the first to third degree, and workers are classified as high occupational risk groups for COVID–19. Ethics. Scientists have conducted the study in compliance with the Ethical principles set out in the Helsinki Declaration of 1975 with amendments of 1983 and obtaining the informed consent of patients. © 2023, Izmerov Research Institute of Occupational Medicine. All rights reserved.
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The emergence, spread, and development of COVID-19 has become a serious challenge and a test of the professional, organizational, and technological capabilities of the global medical community. The specific nature of the profession puts health workers at the forefront of responding to a COVID-19 outbreak and exposes them to a particularly high risk of infection. Hazards include contact with the pathogen, long work hours, psychological distress, fatigue, occupational burnout, and several others. Simultaneously, as members of society, health workers are also exposed to the general risks and influences of a difficult epidemiological situation (e.g., anxiety from uncertainty, lack of information, and general social and economic problems and constraints). As professionals, health workers must demonstrate the unity of opinion, attitude, and action and act as experts for patients on various issues, implementing the state's health care policy. © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.
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PurposeThe unimagined workplace disturbance caused by the Coronavirus, also known as COVID-19, has made many organizations virtual or telework driven workplaces, often without the infrastructure and systems in place to support employees facing these sudden workplace changes (Burrell, 2020). Many stressors accompanied this transition, to include lack of childcare, home-school responsibilities and layoffs and business closings. These stressors have perpetuated concerns for the job and financial security for all workers (Fox, 2020), leading some employees to struggle with the work-life balance out of concern for being laid off due to perceived low productivity (Fox, 2020). This study aims to explore those manifestations.Design/methodology/approachThis qualitative research case study explores the impact COVID-19 induced telework has on their job satisfaction, mental well-being and aspects of organizational commitment to fill a gap in the literature concerning emerging workplace dynamics due to COVID-19 for small real estate businesses in the USA.FindingsThe results of this qualitative research case study provide knowledge and information about the need for small businesses to be resourceful and resilient in the way that they support and engage remote workers. This qualitative research case study explores the impact COVID-19-induced telework has on their job satisfaction, mental well-being and aspects of organizational commitment for small real estate businesses. The analysis of current work-life structures through a qualitative lens provides trends among workers to gain a greater perspective of the current accelerators and barriers to worker success in a COVID-19 teleworking environment.Originality/valueThis qualitative research case study explores the impact COVID-19 induced telework has on their job satisfaction, mental well-being and aspects of organizational commitment to fill a gap in the literature concerning emerging workplace dynamics due to COVID-19 for small real estate businesses. The value of this research is that majority of the participants were African-Americans, which represents a participant group that is highly under researched.
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Introduction : Understanding the epidemiological and clinical profile of COVID-19 cases and pattern of disease is very much required for future preparedness. Objective : To assess the epidemiological and clinical profile of cases of COVID 19 Method : Cross sectional descriptive study was carried out at a Rural Health Training Centre (RHTC). All cases reported in the month of January 2022were included in the study. The information about the epidemiological and clinical profile was collected from RHTC records by conducting telephonic interview. Results : Total 83 cases were reported. Among them, 43 (54.4%) cases were in age group 20-39 years. Male: Female ratiowas 1.37:1. Therewas one death and patient had ovarian cancer as co-morbidity. Total 71 patients could be contacted for telephonic interview. Fever was most common symptom andwas presenting symptom on first day followed by cough/cold and sore throat. None had shortness of breath or chest pain. Hospitalization rate was 5.63% and none required oxygen supplementation or intensive care. Recovery period was 3-5 days. Out of total, 90% cases were fully vaccinated and 95.8% had knowledge of CAB. Diabetes and hypertension were most common comorbidities andwere statistically significantlymore in age > 40 years. Conclusions : The COVID-19 cases in the beginning of year 2022 had clinical presentation different than the earlier waves. Periodic situational analysis can guide in policymaking for handling this pandemic in future.
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Coronavirus disease 2019 (COVID-19) has been admitted by WHO as a global pandemic. The successes-ness in controlling COVID-19 is extremely affected by the knowledge and perception of society. Apothecary students must be competent in carrying out the health promotion effort;one of them is through education. Discovering the impact of education from apothecary students in improving knowledge and perception of the society in controlling COVID-19. One group Quasi-experimental design without a control group (n=102). The data was conducted in March-April 2020 using a validated questionnaire containing the respondents' demographic, knowledge, and perception of COVID-19. This research is 18 years old, does not work as a health worker/medical personnel, domiciled in Yogyakarta, and fills up the pre-test and post-test questionnaire. The data were analyzed descriptively and used the Wilcoxon test (p<0.05) as the statistic test. Most respondents are 52.9% women, 34.31% aged 36-45, with 52.94% having a high school education level. The survey result shows that 71.57% of respondents admit that they know about COVID-19 from television and 2.43% from social media. The answer distribution of questioner on knowledge and perception shows improvements in the pre-test and post-test scores. The Wilcoxon test result, the influence of education on respondents' knowledge and perception, shows the significance of p value=0.000 with the outcome of pre-test and post-test scores with the good category are 67.65% and 5.29%. The presentation of education from apothecary students significantly influences society's knowledge and perception of controlling COVID-19.
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This paper attempts to understand the impacts and fallouts of COVID- 19 on health care workers. The effect of social intelligence, emotional stability and optimistic approach are studied on the quality of work of healthcare workers along with identifying how it influenced their job satisfaction. The moderating effect of corona fear is analyzed on the quality of work and job satisfaction. Empirical data derived through face-to-face interactions with 493 health care professionals were used for testing the conceptual framework derived from recent literature. The results indicate that social intelligence, emotional stability and optimism contribute towards quality of life of health care workers. Quality of work shows significant relation with job satisfaction. Corona fear shows the moderation effect, negatively affecting the quality of work.